Research Article

Sensitivity of multiresistant bacteria and methicillin-resistant Staphylococcus aureus to ethanolic root extract of Raphanus sativus

Authors: Dejan Stojković (University of Belgrade, Institute for Biological Research “Siniša Stankovic”, Department of Plant Physiology, Belgrade, ISerbia) , Marija Smiljković (University of Belgrade, Institute for Biological Research “Siniša Stankovic”, Department of Plant Physiology, Belgrade, Serbia) , Miloš Nikolić (University of Belgrade, Institute for Biological Research “Siniša Stankovic”, Department of Plant Physiology, Belgrade, ISerbia) , Jelena Živković (Institute for Medicinal Plant Research “Dr. Josif Pančić”, Belgrade, Serbia) , Marina Soković (University of Belgrade, Institute for Biological Research “Siniša Stankovic”, Department of Plant Physiology, Belgrade, ISerbia)

  • Sensitivity of multiresistant bacteria and methicillin-resistant Staphylococcus aureus to ethanolic root extract of Raphanus sativus

    Research Article

    Sensitivity of multiresistant bacteria and methicillin-resistant Staphylococcus aureus to ethanolic root extract of Raphanus sativus

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Abstract

Raphanus sativus L. (Brassicaceae) is an edible plant, whose root is consumed all over the world. The objective of this study was to test antibacterial potential of R. sativusethanolic extract on 12 pathogenic bacteria including multiresistant bacterial strains and MRSA. All of the tested bacteria showed sensitivity to the antibacterial effect of R. sativusethanolic extract with minimum inhibitory (MIC) and minimum bactericidal concentrations (MBC) in range of 15µg/mL – 500µg/mL. It is interesting to note that raphanus extract showed the highest activity against multiresistant strain of Pseudomonas aeruginosa with equal inhibitory and bactericidal concentrations of 15µg/mL, while the most resistant strain to the effect of the extract was Proteus mirabilis (MIC and MBC of the extract were 300 µg/mL and 500µg/mL, respectively). In disk diffusion assay, zones of inhibitions were measured ranging from 8 mm to 22 mm.

Keywords: Raphanus sativus, ethanolic extract, antibacterial, multiresistant, methicillin-resistant

How to Cite:

Stojković, D., Smiljković, M., Nikolić, M., Živković, J. & Soković, M., (2018) “Sensitivity of multiresistant bacteria and methicillin-resistant Staphylococcus aureus to ethanolic root extract of Raphanus sativus”, Lekovite Sirovine 38(1), 35-38. doi: https://doi.org/10.5937/leksir1838035s

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Published on
2018-12-25

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