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Originalan naučni rad– Original scientific paper

CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF PEPPERMINT ESSENTIAL OIL (Mentha piperita L.)

Authors: Miloš Nikolić (Institute for Biological Research ”Siniša Stanković“, Belgrade, Serbia) , Jasmina Glamočlija (Institute for Biological Research ”Siniša Stanković“, Belgrade, Serbia) , Ana Ćirić (Institute for Biological Research ”Siniša Stanković“, Belgrade, Serbia) , Tatjana Marković (Institute for Medicinal Plant Research ”Dr Josif Pančić”, Belgrade, Serbia) , Dejan Marković (University of Belgrade, Faculty of Dental Medicine, Department of Pediatric and Preventive Dentistry, Belgrade, Serbia) , Tamara Perić (University of Belgrade, Faculty of Dental Medicine, Department of Pediatric and Preventive Dentistry, Belgrade, Serbia) , Marina Soković (Institute for Biological Research ”Siniša Stanković”, Belgrade, Serbia)

  • CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF PEPPERMINT ESSENTIAL OIL (Mentha piperita L.)

    Originalan naučni rad– Original scientific paper

    CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF PEPPERMINT ESSENTIAL OIL (Mentha piperita L.)

    Authors: , , , , , ,

Abstract

The aim of this study was to investigate the chemical composition and antimicrobial activity of essential oils of peppermint Mentha piperita L. GC / MS techniques confirmed the presence of the 48 components of which menthol (35.57 %) and menthone (22.50 %) were the most abundant. Antimicrobial activity, ie the minimum inhibitory and minimum bactericidal / fungicidal (MIC, MBC/MFC) concentrations were obtained using the mikordilution method against pathogenic microorganism isolated from the oral cavity (8 bacteria and 58 Candida sp.) and referent strains. The essential oil of peppermint showed good antimicrobial activity with MIC from 0.63 to 5 mg / ml and 0.13 to 0.5 for bacteria and fungi and MBC 1.25 to 10 mg / ml , ie. MFC 0.5-1 mg / ml. Compared to Hexoral®, peppermint essential oil has a very strong antimicrobial potential. The results of these tests give a new value, which will enrich the knowledge of peppermint oil od presented chemical composition, opens the door for further research towards its use in dentistry and as well in prevention and treatment of various diseases caused by tested pathogens.

Keywords: essential oil; peppermint; Mentha piperita L.; antimicrobial activity

How to Cite:

Nikolić, M., Glamočlija, J., Ćirić, A., Marković, T., Marković, D., Perić, T. & Soković, M., (2013) “CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF PEPPERMINT ESSENTIAL OIL (Mentha piperita L.)”, Lekovite Sirovine 33(1), 63–72.

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Published on
2013-12-31

Peer Reviewed