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Research Article

Inhibition of microbial biofilm formation by Cydonia oblonga Mill. fruit peel and leaf ethanolic extracts

Authors: Dejan Stojković (University of Belgrade, Institute for Biological Research “Siniša Stanković”, Belgrade, Serbia) , Kristina Jevremović (University of Belgrade, Institute for Biological Research “Siniša Stanković”, Belgrade, Serbia) , Marija Smiljković (University of Belgrade, Institute for Biological Research “Siniša Stanković”, Belgrade, Serbia) , Jelena Živković (Institute for Medicinal Plant Research “Dr. Josif Pančić”, Belgrade, Serbia) , Marina Soković (University of Belgrade, Institute for Biological Research “Siniša Stanković”, Belgrade, Serbia)

  • Inhibition of microbial biofilm formation by Cydonia oblonga Mill. fruit peel and leaf ethanolic extracts

    Research Article

    Inhibition of microbial biofilm formation by Cydonia oblonga Mill. fruit peel and leaf ethanolic extracts

    Authors: , , , ,

Abstract

This study aimed to investigate the activity of  C. oblonga peel and leaf ethanolic extracts on biofilm formation of different microbial strains, including pathogenic bacteria and food poisoning strains. It was shown that both of the investigated extracts inhibited biofilm formation in a dose dependent manner with sub-minimal inhibitory concentrations. The percentage of biofilm formation inhibition varied for each bacterial strain and was in the range of 10-100%, for both of the tested extracts. The ability of extracts to inhibit already formed biofilms presented as minimal concentration necessary to disrupt biofilms and concentrations was in the range of 0.010-0.100 mg/mL for the leaf extract and 0.005-0.075 mg/mL for the peel extract. The investigated extracts showed a promising antimicrobial effect comparable to, or even higher than the used reference compounds which make these plant parts attractive for pharmaceutical and food industry.

Keywords: Cydonia oblonga, biofilm, antibacterial, peel

How to Cite:

Stojković, D., Jevremović, K., Smiljković, M., Živković, J. & Soković, M., (2018) “Inhibition of microbial biofilm formation by Cydonia oblonga Mill. fruit peel and leaf ethanolic extracts”, Lekovite Sirovine 38(1), 58-61. doi: https://doi.org/10.5937/leksir1838058s

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Published on
2018-12-25

Peer Reviewed