Sonication of smoke tree extract-loaded liposomes: the antioxidant potential of particles
Authors:
Aleksandra Jovanović
(Institute for the Application of Nuclear Energy INEP, University of Belgrade, Belgrade, Serbia)
,
Milena Milošević
(Institute of Chemistry, Technology, and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)
,
Miroslav Novaković
(Institute of Chemistry, Technology, and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)
,
Aleksandar Marinković
(Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia)
Abstract
With the aim to examine the radical scavenging activity of smoke tree extract-loaded liposomal particles before and after ultrasound exposure (45 or 70% amplitude and 15 or 30 min), ABTS and DPPH tests were employed. The antioxidant activity of the pure extract was 11.37 ± 0.52 μmol Trolox equivalent (TE)/mL and 79.7 ± 0.5%. Multilamellar liposomes with extract showed significantly higher antioxidant activity in both assays (12.02 ± 0.54 μmol TE/mL and 81.9 ± 0.4%) compared to sonicated liposomes (10.75-11.00 μmolTE/mL and 79.3-80.9%) and pure extract. There was no significant difference between the ABTS radical scavenging activity of the liposomes treated by different amplitudes and times, while prolonged sonication and a higher amplitude caused a significant drop in the anti-DPPH capacity of extract-loaded liposomal vesicles. The presented results and the differences between the obtained data provide a good insight into the overall antioxidant capacity of smoke tree extract-loaded multilamellar and sonicated unilamellar liposomal vesicles.
Keywords: antioxidants, liposomes, smoke tree, sonication
How to Cite:
Jovanović, A., Milošević, M., Novaković, M. & Marinković, A., (2024) “Sonication of smoke tree extract-loaded liposomes: the antioxidant potential of particles”, Lekovite Sirovine 44(1), 1-3. doi: https://doi.org/10.61652/leksir2444003j
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