Research Article
Authors: Ivana Živković (University of Belgrade, Faculty of Agriculture, Institute for Food Technology and Biochemistry, Belgrade, Serbia) , Katarina Šavikin (Institute for Medicinal Plants Research “Dr. Josif Pančić”, Belgrade, Serbia) , Gordana Zdunić (Institute for Medicinal Plants Research “Dr. Josif Pančić”, Belgrade, Serbia) , Jelena Živković (Institute for Medicinal Plants Research “Dr. Josif Pančić”, Belgrade, Serbia) , Dubravka Bigović (Institute for Medicinal Plants Research “Dr. Josif Pančić”, Belgrade, Serbia) , Nebojša Menković (Institute for Medicinal Plants Research “Dr. Josif Pančić”, Belgrade, Serbia) , Dragoslav Radin (University of Belgrade, Faculty of Agriculture, Institute for Food Technology and Biochemistry, Belgrade, Serbia)
Medicinal plant extracts have a broad antimicrobial activity, including antiviral effects. In our study, eleven dry extracts of ten different medicinal plants prepared with two solvents (5%, dimethyl sulfoxide (DMSO) and 30% ethanol in 5% DMSO) in different concentrations have been examined for anti-norovirus activity. The reduction of norovirus &gt;1 log10 genome equivalents has been obtained with 1 mg/mL of Aronia melanocarpa leaf extract, dried wine Prokupac and Hypericum perforatum extract. Some of the observed extracts i.e. Hypericum perforatum , Aronia melanocarpa fruit extract and Punica granatum peel extract showed better activity when dissolved in 30% ethanol with 5% DMSO. All results of anti-noroviral activity of tested extracts which achieved &lt;0.5 log10 genome equivalents were considered as not effective.<br />&nbsp;
Keywords: Human norovirus, medicinal plant extract, antiviral activity
How to Cite: Živković, I. , Šavikin, K. , Zdunić, G. , Živković, J. , Bigović, D. , Menković, N. & Radin, D. (2018) “Antiviral activity of medicinal plants extracts against foodborne norovirus”, Lekovite Sirovine. 38(1). doi: https://doi.org/10.5937/leksir1838031z