Exploring the attitude of Faculty of Medicine students about herbal products usage: a cross-sectional study

Emilija Kostić, Milica Milutinović, Milica Kostić, Jasmina Petrović, Bojana Miladinović, Suzana Branković, Maja Vujović, Dusanka Kitic

DOI: http://dx.doi.org/10.5937/leksir1939069K


Herbal products have gained popularity, and they are often perceived as safe. The roles of the pharmacists and physicians are essential in the proper usage of those products. This study aimed to investigate the students of Faculty of Medicine in Niš about the use of herbal preparations and the differences between medicine, pharmacy and dentistry students. The fifth-year university students were questioned through an anonymous survey. The obtained results were processed statistically and presented graphically. The majority of the students would prefer a combination of herb product and drug (76.9%). Usage of herbal products is based on students' knowledge, on the advice of pharmacists, family members, physicians, and the media. The majority of students purchase herbal products in the pharmacy and nobody obtained them via the Internet. Most of the students used them in preventive purposes (60%) and claimed that there were positive effects. Students (75%) read the instructions for use and side effects, especially pharmacy students (88.3%). Medicine students (60%) consider herbal products completely safe. Pharmacy students are considered to receive the necessary knowledge on herbal products (68.3%), while a smaller percentage of medicine and dentistry students consider the same. Students use herbal medicines but are not entirely familiar with their effects and safety. There is a need for raising awareness, the importance of side effects and interactions of herbs and drugs among medicine and dentistry students. This goal can be achieved by changing curriculum which would contain material from phytotherapy.


herbal products; survey; attitude; students; Faculty of Medicine; Niš

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Ameade, EP., Amalba, A., Helegbe, GK. and Mohammed, BS. (2015). Herbal medicine: a survey on the knowledge and attitude of medical students in Tamale, Ghana. Peak Journal of Medicinal Plant Research 3(1), 1-8.

Bauer, B. A. (2000). Herbal therapy: what a clinician needs to know to counsel patients effectively. Mayo Clin. Proc. 75(8), 835–841. https://doi.org/10.4065/75.8.835

Bent, S. (2008). Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medicine Center. J. Gen. Intern. Med. 23(6), 854–859. https://doi.org/10.1007/s11606-008-0632-y

Booker, A., Johnston, D. and Heinrich, M. (2015). Value Chains of Herbal Medicines— Ethnopharmacological and Analytical Challenges in a Globalizing World, in: Mukherjee, P.K. (Ed.), Evidence-Based Validation of Herbal Medicine. Elsevier, Amsterdam, pp. 29–44. https://doi.org/10.1016/b978-0-12-800874-4.00002-7

Boparai, J., Singh, A., Gupta, A., Matreja, P., Khanna, P., Gupta, V. and Gautam, R. (2017). A study to determine the knowledge and level of awareness of medicine undergraduates about herbal medicines and herb-drug interactions. Int. J. Basic Clin. Pharmacol. 6(1), 17–24. https://doi.org/10.18203/2319-2003.ijbcp20164509

Builders, P. (2018). Introductory Chapter: Introduction to Herbal Medicine, in: Builders, P. (Ed.), Herbal Medicine. IntechOpen, London. http://dx.doi.org/10.5772/intechopen.78661

Chekole, G. (2017). Ethnobotanical study of medicinal plants used against human ailments in Gubalafto District, Northern Ethiopia. J. Ethnobiol. Ethnomed. 13(1), 55. https://doi.org/10.1186/s13002-017-0182-7

Clement, Y.N., Morton-Gittens, J., Basdeo, L., Blades, A., Francis, M.J., Gomes, N. and Singh, A. (2007). Perceived efficacy of herbal remedies by users accessing primary healthcare in Trinidad. BMC Complement. Altern. Med. 7, 4. https://doi.org/10.1186/1472-6882-7-4

Clement, Y.N., Williams, A.F., Khan, K., Bernard, T., Bhola, S., Fortuné, M. and Seaforth, C.E. (2005). A gap between acceptance and knowledge of herbal remedies by physicians: The need for educational intervention. BMC Complement. Altern. Med. 5, 20. https://doi.org/10.1186/1472-6882-5-20

Corrêa da Silva, M.G., da Silva, M.G.C., Soares, M.C.F. and Muccillo-Baisch, A.L. (2012). Self-medication in university students from the city of Rio Grande, Brazil. BMC Public Health, 12, 339. https://doi.org/10.1186/1471-2458-12-339

Ćujić, N., Ibrić, S., Bigović, D., Noveski, N. and Šavikin, K. (2015) Stability testing of herbal medicines. Lek. Sirov. 35, 53-60. http://dx.doi.org/10.5937/leksir1535053C

Ekor, M. (2014). The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front. Pharmacol. 4, 177. doi:10.3389/fphar.2013.00177

Fakeye, T.O. and Onyemadu, O. (2008). Evaluation of knowledge base of hospital pharmacists and physicians on herbal medicines in Southwestern Nigeria. Pharm Pract, 6(2), 88–92. https://doi.org/10.4321/S1886-36552008000200005

Gardiner, P., Graham, R., Legedza, A.T.R., Ahn, A.C., Eisenberg, D.M. and Phillips, R.S. (2007a). Factors associated with herbal therapy use by adults in the United States. Altern. Ther. Health Med. 13(2), 22–29.

Gardiner, P., Kemper, K. J., Legedza, A. and Phillips, R. S. (2007b). Factors associated with herb and dietary supplement use by young adults in the United States. BMC Complement. Altern. Med. 7, 39. https://doi.org/10.1186/1472-6882-7-39

Howell, L., Kochhar, K., Saywell, R., Zollinger, T., Koehler, J., Mandzuk, C., Sutton, B., Sevilla-Martir, J., Allen, D. (2006). Use of herbal remedies by Hispanic patients: do they inform their physician? J. Am. Board Fam. Med. 19(6), 566–578. https://doi.org/10.3122/jabfm.19.6.566

Kennedy, J., Wang, C.C. and Wu, C.H. (2008). Patient disclosure about herb and supplement use among adults in the US. Evid-Based Compl. Alt. 5(4), 451–456. https://doi.org/10.1093/ecam/nem045

Newberry, H., Beerman, K., Duncan, S., McGuire, M. and Hillers, V. (2001). Use of nonvitamin, nonmineral dietary supplements among college students. J. Am. Coll. Health 50(3), 123–129. https://doi.org/10.1080/07448480109596016

Nur, N. (2010). Knowledge and behaviours related to herbal remedies: a cross-sectional epidemiological study in adults in Middle Anatolia, Turkey. Health Soc. Care Comm. 18(4), 389–395. https://doi.org/10.1111/j.1365-2524.2010.00911.x

Pan, S.Y., Zhou, S.F., Gao, S.H., Yu, Z.L., Zhang, S.F., Tang, M.K., Sun, J.N., Ma, D.L., Han, Y.F., Fong, W.F. and Ko, K.M. (2013). New perspectives on how to discover drugs from herbal medicines: CAM's outstanding contribution to modern therapeutics. Evid-Based Compl. Alt. 2013, 627375. doi:10.1155/2013/627375

Perkin, J. E., Wilson, W. J., Schuster, K., Rodriguez, J. and Allen-Chabot, A. (2002). Prevalence of nonvitamin, nonmineral supplement usage among university students. J. Am. Diet. Assoc. 102(3), 412–414. https://doi.org/10.1016/S0002-8223(02)90096-9

Petrovska B.B. (2012). Historical review of medicinal plants' usage. Pharmacogn. Rev. 6(11), 1–5. doi:10.4103/0973-7847.95849

Saad, B., Azaizeh, H., Abu-Hijleh, G. and Said, O. (2006). Safety of traditional Arab herbal medicine. Evid-Based Compl. Alt. 3(4), 433–439. https://doi.org/10.1093/ecam/nel058

Samojlik, I., Mijatović, V., Gavarić, N., Krstin, S. and Božin, B. (2013). Consumers’ attitude towards the use and safety of herbal medicines and herbal dietary supplements in Serbia. Int. J. Clin. Pharm. 35(5), 835–840. https://doi.org/10.1007/s11096-013-9819-3

Sekhri, K., Bhanwra, S. and Nandha, R. (2013). Herbal products: a survey of students’ perception and knowledge about their medicinal use. Int. J. Basic Clin. Pharmacol. 2(1), 71–76. https://doi.org/10.5455/2319-2003.ijbcp20130114

Sma, A., Abdelmalek, S.M.A., Alkhawaja, B. and Darwish, D.A. (2016). Perceptions and use of medicinal herbs among college students at a Jordanian University in Amman-Jordan: traditions supersedes education. J. Tradi. Med. Clin. Natur. 5(3), 191. https://doi.org/10.4172/2573-4555.1000191

Sofowora, A., Ogunbodede, E., and Onayade, A. (2013) The role and rlace of medicinial plants in the strategies for disease prevention. Afr. J. Tradit. Complement. Altern. Med. 10(5), 210-229.

Stragar, J., Pilih, M., Pogacnik, M. and Znidarcic, D. (2013). Knowledge of medicinal plants and their uses among secondary and grammar school students: A case study from Slovenia. Arch.

Biol. Sci. 65(3), 1123–1129. https://doi.org/10.2298/abs1303123s

Wahner-Roedler, D.L., Vincent, A., Elkin, P.L., Loehrer, L.L., Cha, S.S. and Bauer, B.A. (2006). Physicians’ attitudes toward complementary and alternative medicine and their knowledge of specific therapies: a survey at an academic medicine center. Evid-Based Compl. Alt. 3(4), 495–501. https://doi.org/10.1093/ecam/nel036

Walker, P.S. and Donovan, J.A. (1999). Herbal remedies: natural caveats. Int. J. Dermatol. 38(10), 746–748. https://doi.org/10.1046/j.1365-4362.1999.00825.x

Xu, S. and Levine, M. (2008). Medicine residents’ and students' attitudes towards herbal medicines: a pilot study. Can. J. Clin. Pharmacol. 15(1), e1–e4.

Yoshida, N., Numano, M., Nagasaka, Y., Ueda, K., Tsuboi, H., Tanimoto, T. and Kimura, K. (2015). Study on health hazards through medicines purchased on the Internet: a cross-sectional investigation of the quality of anti-obesity medicines containing crude drugs as active ingredients. BMC Complem. Altern. M. 15(1), 430. https://doi.org/10.1186/s12906-015-0955-2


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Copyright (c) 2019 Emilija Kostić, Milica Milutinović, Milica Kostić, Jasmina Petrović, Bojana Miladinović, Suzana Branković, Maja Vujović, Dusanka Kitic

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