Preliminary safety estimate of cosmetic anti-age creams with chokeberry extract, using in vivo bioengineering techniques

Nada Ćujić, Ana Žugić, Jelena Živković, Katarina Šavikin, Gordana Zdunić



Potential of anti-age cosmetic line, day and night creams was evaluated using noninvasive measurements of the appropriate skin biophysical parameters in a 24-h in vivo study under occlusion. Thirty one healthy female volunteers were involved in the study. Electrical capacitance (EC), transepidermal water loss (TEWL), erythema index (EI) were evaluated. Preliminary safety prolife of the investigated creams with natural origin ingredients based on obtained results can be considered satisfactory. The stated samples did not cause the change in the measured biophysical parameters-TEWL and EI, while they incresed EC i.e. stratum corneum hydration. These results suggest that chokeberry extract and other natural ingredients could exert beneficial effects and has potential on aged skin thereby slowing down the appearance of wrinkles and their existing alleviation, and they could be considered prefferable in the cosmetic products intened for the treatment of aged skin.


chokeberry, polyphenols, anthocyanins, antioxidants, anti-age

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