Biological activities of Sorbus aucuparia L. leaves extract

Katarina Šavikin, Zdunić Gordana, Alimpić Ana, Dubravka Bigović, Dejan Pljevljakušić, Sonja Duletić-Laušević



Biological activities of Sorbus aucuparia L. leaves extract was tested in our study. Antineurodegenerative activity was evaluated by acetylcholinesterase (AChE) and tyrosinase (TYR) inhibitory activity assays while antioxidant activity was by tested using four different assays. In all antioxidant test we noticed concentration dependent activity of tested extract and the highest applied concentration of 500 μg/ml was the most active. Extract applied in concentration of 200 μg/ml showed higher percent of inhibition in DPPH test compared to both applied concentrations of standard substances BHA and BHT (50 and 100 μg/ml). In ABTS test, activity of extract applied in 500 μg/ml was comparable or higher then BHA and BHT/Vitamin C, respectively. Moreover, all concentrations of tested extract were significantly more active in ß-carotene test than vitamin C. The lowest concentration of extract (100 μg/ml) was the most active in TYR assay reaching 42.57 % of the inhibition while in AChE assay there was not statistically significant differences among all applied concentrations.


Sorbus aucuparia, dry extract, antioxidant activity, antineurodegenerative activity

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