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Edited by:

Dr. Milan Lukić

Vol 43, No 1 (2023):

Lekovite Sirovine

Published: 25.12.2023.

Current issue
10.12.2023. Research Article
Microwawe–assisted extraction of antioxidant compounds from Vaccinium Myrtillus leaves

By Muna Elferjane, Petar Batinić, Natalija Čutović, Milena Milošević, Vojislav Ćirić, Aleksandar Marinković, Aleksandra Jovanović

22.12.2023. Research Article
Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes

By Natalija Cutovic, Tatjana Marković, Ana Žugić, Petar Batinic, Branko Bugarski, Aleksandra Jovanović

29.12.2023. Research Article
Liposomes as a carrier for 4–hydroxycoumarin: characterisation, stability and antioxidant potential

By Aleksandra Jovanović, Edina Avdović, Ana Plećić, Vojislav Ćirić, Branko Bugarski, Zoran Marković

19.12.2023. Review Article
Usage areas, biological activities and volatile oil compounds of Matricaria aurea and Matricaria chamomilla

By Hasan Hüseyin Yaz, İmran Uysal, Abdullah Ozan Polat, Falah Saleh Mohammed, Mustafa Sevindik

23.12.2023. Research Article
Developed and validated HPLC method for simultaneous analysis of key flavonoids and phenolcarboxylic acids in the hawthorn-based cardiotonic Forticor®

By Vanja Tadic, Dragica Bojovic, Goran Marković, Ivana Nešić, Ana Žugić

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27.12.2013. Originalan naučni rad– Original scientific paper

By Sandra Đorđević, Tatjana Marković, Sava Vrbničanin, Dragana Božić

Ambrosia artemisiifolia L. is an allergen species that belongs to the group of invasive weeds, and is very frequent and present in our region. The use of essential oils in the control of weeds attracts great attention of researchers. Many of them have already pointed out the ability of some oils and/or their individual components to delay seed germination of various weeds or completely inhibit it. In this paper, we present results of the efficacy of three essential oils on A. artemisiifolia seeds; the trials were carried out using two different in vitro methods, in which the percentage of seed germination was measured 7th day.  In testings with seeds soaked in essential oil solution, in Petri dishes (500 ml in 100 ml of distilled water), a significant inhibition of germination was observed in the case A. graveolens and S. officinalis oil (100 % and 97 % , respectively), while the oil of S. montana demonstrated slightly weaker inhibitory effect (86 %). When essential oils were applied in form of a vapour (an oil droplet of 25 ml applied on the inner side od Petri dish lids), A. graveolens and S. officinalis oils inhibited the seed germination 100 % and and 95 % , respectively , while the oil of S. montana again demonstrated the weakest inhibitory effect (52 %).

The aim of the presented research was to determine whether the application of the essential oils of A. graveolens, S. officinalis and S. montana in form of a solution or vapor, affects, and to what extent they are important for germination of seeds of the weed species A. artemisiifolia L.

25.12.2021. Research Article
Microwave-assisted extraction of essential oil from ginger (Zingiber officinale Rosc.)

By Zorica Drinić, Miloš Jovanović, Dejan Pljevljakušić, Nada Čujić-Nikolić, Dubravka Bigović, Katarina Šavikin

25.12.2021. Research Article
Evaluation of antioxidant activities and haematological effects of Asystasia gangetica leaf extract in monosodium glutamate-treated rats

By Robert Uroko, Amarachi Agbafor, Simeon Egba, Chinedu Nwuke, Sharon Kalu-Kalu

31.12.2013. Originalan naučni rad– Original scientific paper
SEED QUALITY AND SWELLING INDEX OF MARSHMALLOW (Althaea officinalis L.), LINSEED (Linum usitatissimum L.) AND FENUGREEK (Trigonella foenum graecum L.) SEED

By Vladimir Filipović, Vera Popović, Đorđe Glamočlija, Tatjana Marković, Dragoja Radanović, Vladan Ugrenović, Violeta Mickovski Stefanović

This paper presents different quality parameters of the seeds of three cultivated medicinal plant species investigated: marshmallow (Althaea officinalis L.), flax (Linum usitatissimum L.) and fenugreek (Trigonella foenum graecum L.). For determination of agronomic and Pharmacopoeial parameters, different aged seeds, collected during six year period (2008 – 2013), were used. Flax seeds (Lini semen) and fenugreek seeds (Trigonellae foenugraeci semen) are considered as official herbal drugs, but not the marshmallow seeds (Althaeae semen). Following agronomic seed quality parameters were determined: germination energy, total germination, 1000-seed weight, and swelling index. The highest average germination parameters was recorded with fenugreek seed (EC = 97.7 % and UK = 97.8 %), quite lower were in flax seeds (EC = 75.2 % and UK = 80.7 %), while the lowest were in marshmallow seeds (EC = 8.1% and UK = 19.8%). 1000-seed weight of the flax and fenugreek were in agreement with previous research. The greatest average swelling index was achieved in flax seeds (6.5 ml), being higher by 38.5% in comparison to prescribed minimum (4 ml), while the average swelling index of fenugreek seeds was 6.2 ml, also exceeding the prescribed minimum, but slightly (6 ml). The avarage swelling index for marshmallow seeds was 5.4 ml. Although the Althaeae semen is not an officinal herbal drug, a six-year data on the swelling index of the seeds can be used as reference values in the further definition of a new Pharmacopoeial standard for this herbal drug.


25.12.2017. Research Article
Phytochemical characterization and antioxidant potential of rustyback fern (Asplenium ceterach L.)

By Suzana Živković, Marijana Skorić, Branislav Šiler, Slavica Dmitrović, Biljana Filipović, Tijana Nikolić, Danijela Mišić

25.12.2018. Research Article
Effect of extraction solvent on total polyphenols content and antioxidant activity of Cannabis sativa L.

By Zorica Drinić, Senka Vidović, Jelena Vladić, Anamarija Koren, Biljana Kiprovski, Vladmir Sikora

25.12.2021. Research Article
Evaluation of different solvents for phytochemical constituents and antioxidant activities of the leaves of Acanthus montanus (Nees) T. Anderson

By Ale Joy Enitan, Lawal Ibraheem Oduola, Omogbene Temitope Olorunyomi

Bear’s breech or mountain thistle (Acanthus montanus (Nees) T. Anderson) is a shrub belonging to Acanthaceae family. It is widespread in Africa, Romania, Greece, and Eastern Mediterranean. African people engage its medicinal use for the management of urethral pain, endometritis, urogenital infections, urinary disease, aches and pains. Fresh leaves of A. montanus were collected from Forestry Research Institute of Nigeria (FRIN) herbal garden and identified at the Forestry Herbarium, Ibadan. About 200 g of the powered sample was macerated in 400 mL each of three organic solvents such as ethyl acetate, acetone and methanol respectively, for 24 h. Each extracts were screened for phytochemicals such as flavonoids, saponins, phenols, terpenoids, phlobotannins, alkaloids, tannins, and cardiac glycosides. Estimation of total flavonol content, and antioxidant assays such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) and nitric oxide radical scavenging activity were also carried out. The quantitative phytochemical test (flavonol content) revealed that Acanthus montanus methanol extract was the richest one among the solvent systems while acetone extract gave the best antioxidant activity. It was observed that the antioxidant activity could be attributed to moderately polar extracts. The study, therefore, provides evidence that various solvents used in extraction can result in differences in quantitative phytochemicals and antioxidant activity.


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