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Qualitative and quantitative phytochemical evaluation of Quassia undulata (Guill. & Perr.) D. Dietr. leaves using different solvent polarities

By
Ibraheem Oduola-Lawal ,
Ibraheem Oduola-Lawal
Contact Ibraheem Oduola-Lawal

Biomedicinal Research Centre, Forestry Research Institute of Nigeria, Oyo State, Nigeria

Adeniyi Olufunso ,
Adeniyi Olufunso

Biomedicinal Research Centre, Forestry Research Institute of Nigeria, Oyo State, Nigeria

Montane Forest Research Station, Forestry Research Institute of Nigeria, Palateau State, Nigeria

Ariwoola Oluwole
Ariwoola Oluwole

Montane Forest Research Station, Forestry Research Institute of Nigeria, Plateau State, Nigeria

Biomedicinal Research Centre, Forestry Research Institute of Nigeria, Oyo State, Nigeria

Abstract

This study investigated solvent effects on the phytochemical composition of Quassia undulata leaves a medicinal plant used in treating arrays of diseases including fever and cough. The leaves were collected, washed, air-dried, pulverized and evaluated for some inherent phytochemicals using four different solvent systems based on their polarities. The solvents are methanol, acetone, ethyl acetate and chloroform. The methanol extract was found to have the highest number of secondary metabolites (saponins, tannins, flavonoids, steroids, coumarins, anthraquinones, alkaloids and phenols). None of the extracts tested positive for the presence of phlobatannins, terpenoids and emodins. The methanol extract was further analyzed quantitatively for some of the determined phytochemicals. Tannins had a concentration of 3.131 mg of catechin equivalents per 100 mg sample (mg CE/100g), alkaloids - 5.200 %, total phenolics - 11.828 mg of gallic acid equivalents per gram of extract (mg GAE/g), flavonoids - 8.074 mg of quercetin equivalents per gram of extract (mg QE/g) while 0.673 % saponins were detected. The presence of these secondary metabolites might justify the ethnomedicinal uses of Quassia undulata leaves as their bioactivity has been found to be dependent on the solvent used for extraction.


 

References

[{"id":4277,"citationNumber":"1.","type":"article-journal","title":"Natural polyphenols: An overview","DOI":null,"author":[{"given":"M.","family":"Abbas"},{"given":"F.","family":"Saeed"},{"given":"F.M.","family":"Anjum"},{"given":"M.","family":"Afzaal"},{"given":"T.","family":"Tufail"},{"given":"M.S.","family":"Bashir"},{"given":"A.","family":"Ishtiaq"},{"given":"S.","family":"Hussain"},{"given":"H.A.R.","family":"Suleria"}],"issued":{"date-parts":["2017"]},"container-title":"International Journal of Food Properties","volume":"20","issue":"8","page":"1689\u2013 1699"}]

[{"id":4278,"citationNumber":"2.","type":"chapter","title":"Polyphenols: Properties, occurrence, content in food and potential effects","DOI":null,"author":[{"given":"H.","family":"Abdel-Shafy"},{"given":"M.","family":"Mansour"}],"issued":{"date-parts":["2017"]},"container-title":"Environmental Science and Engineering (Multi-Volume Set), Studium Press LLC","volume":null,"issue":null,"page":"232\u2013261"}]

[{"id":4279,"citationNumber":"3.","type":"article-journal","title":"Composition and evaluation of nutritional, anti-nutritional properties of Quassia undulata","DOI":null,"author":[{"given":"O.","family":"Adeniyi"},{"given":"I.","family":"Lawal"}],"issued":{"date-parts":["2020"]},"container-title":"D Dietr leaves, Journal of Forestry Research and Management","volume":"17","issue":"1","page":"67\u201371"}]

[{"id":4280,"citationNumber":"4.","type":"article-journal","title":"Extraction and characterization of underutilized seed oils sampled in South-Western Nigeria","DOI":null,"author":[{"given":"O.O.","family":"Adeniyi"}],"issued":{"date-parts":["2019"]},"container-title":"International Annals of Science","volume":"7","issue":"1","page":"48\u201352"}]

[{"id":4281,"citationNumber":"5.","type":"article-journal","title":"In vivo antimalarial activities of Quassia amara and Quassia undulata plant extracts in mice","DOI":null,"author":[{"given":"E.O.","family":"Ajaiyeoba"},{"given":"U.I.","family":"Abalogu"},{"given":"H.C.","family":"Krebs"},{"given":"A.M.","family":"Oduola"}],"issued":{"date-parts":["1999"]},"container-title":"Journal of Ethnopharmacology","volume":"67","issue":"3","page":"321\u2013325"}]

[{"id":4282,"citationNumber":"6.","type":"article-journal","title":"Antimicrobial activity of crenatine, an alkaloid synthesized from indole","DOI":null,"author":[{"given":"E.O.","family":"Ajayeoba"},{"given":"B.A.","family":"Adeniyi"},{"given":"J.I.","family":"Okogun"}],"issued":{"date-parts":["1995"]},"container-title":"Phytotherapy Research","volume":"9","issue":"1","page":"69\u201371"}]

[{"id":4283,"citationNumber":"7.","type":"article-journal","title":"Phytochemical profile and antimicrobial potential of methanolic extracts of bark and leaf of Quassia indica (Gaertn","DOI":null,"author":[{"given":"P.","family":"Anusha"},{"given":"B.R.","family":"Sudha"}],"issued":{"date-parts":["2017"]},"container-title":"Nooteb., The Journal of Phytopharmacology","volume":"6","issue":"5","page":"269\u2013276"}]

[{"id":4284,"citationNumber":"8.","type":"article-journal","title":"A systematic review of Iran\u2019s medicinal plants with anticancer effects","DOI":null,"author":[{"given":"M.","family":"Asadi-Samani"},{"given":"W.","family":"Kooti"},{"given":"E.","family":"Aslani"},{"given":"H.","family":"Shirzad"}],"issued":{"date-parts":["2016"]},"container-title":"Journal of Evidence-Based Complementary & Alternative Medicine","volume":"21","issue":"2","page":"143\u2013153"}]

[{"id":4285,"citationNumber":"9.","type":"article-journal","title":"Extraction of some secondary metabolites &thin layer chromatography from different parts of Centella asiatica L","DOI":null,"author":[{"given":"S.R.","family":"Biradar"},{"given":"B.D.","family":"Rachetti"}],"issued":{"date-parts":["2013"]},"container-title":"URB), American Journal of Life Sciences","volume":"1","issue":"6","page":"243\u2013247"}]

[{"id":4286,"citationNumber":"10.","type":"article-journal","title":"Anthraquinones benefits and side effects","DOI":null,"author":[{"given":"B.","family":"Bolen"},{"given":"E.","family":"Chukwuebuka"},{"given":"I.J.","family":"Chinenye"}],"issued":{"date-parts":["2020"]},"container-title":"IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS","volume":"10","issue":"2","page":"10\u201319"}]

[{"id":4287,"citationNumber":"11.","type":"article-journal","title":"Potentials of aqueous extract of pod husk Parkia biglobosa (Jacq.) Benth as a biopesticide in Okra (Abelmoschus esculentus (L","DOI":null,"author":[{"given":"O.","family":"Fayinminnu"},{"given":"O.","family":"Adeniyi"},{"given":"O.","family":"Alabi"},{"given":"D.","family":"Omobusuyi"}],"issued":{"date-parts":["2017"]},"container-title":"Moench) production, Journal of Agriculture and Ecology Research International","volume":"12","issue":"1","page":"1\u201312"}]

[{"id":4288,"citationNumber":"12.","type":null,"title":"Quassia undulata (Guill. & Perr.) D.Dietr., [Internet] Record from PROTA4U. Louppe, D","DOI":null,"author":[{"given":"J.","family":"Gyakari"},{"given":"J.","family":"Cobbinah"}],"issued":{"date-parts":["2008"]},"container-title":null,"volume":null,"issue":null,"page":null}]

[{"id":4289,"citationNumber":"13.","type":null,"title":"PROTA (Plant Resources of Tropical Africa \/ Ressources v\u00e9g\u00e9tales de l\u2019Afrique tropicale","DOI":null,"author":[],"issued":{"date-parts":[null]},"container-title":null,"volume":null,"issue":null,"page":null}]

[{"id":4290,"citationNumber":"14.","type":"book","title":"Phenolic Compounds","DOI":null,"author":[{"given":"J.B.","family":"Harborne"}],"issued":{"date-parts":["1984"]},"container-title":null,"volume":null,"issue":null,"page":"37\u201399"}]

[{"id":4291,"citationNumber":"15.","type":"article-journal","title":"Anthocyanins: natural colorants with health-promoting properties","DOI":null,"author":[{"given":"J.","family":"He"},{"given":"M.M.","family":"Giusti"}],"issued":{"date-parts":["2010"]},"container-title":"Annual Review of Food Science and Technology","volume":"1","issue":null,"page":"163\u2013187"}]

[{"id":4292,"citationNumber":"16","type":"article-journal","title":"Physicochemical characterization of Quassia undulata seed oil for biodiesel production","DOI":null,"author":[{"given":"W.","family":"Iko"},{"given":"S.O.O.","family":"Eze"}],"issued":{"date-parts":["2012"]},"container-title":"African Journal of Biotechnology","volume":"11","issue":"83","page":"14930\u201314933"}]

[{"id":4293,"citationNumber":"17.","type":"article-journal","title":"Phytochemicals investigation on a tropical plant, Syzygium cumini from Kattuppalayam, Erode district, Tamil Nadu","DOI":null,"author":[{"given":"A.","family":"Kumar"},{"given":"R.","family":"Ilavarasan"},{"given":"T.","family":"Jayachandr"},{"given":"M.","family":"Decaraman"},{"given":"P.","family":"Aravindhan"},{"given":"N.","family":"Padmanabha"},{"given":"M.","family":"Krishnan"}],"issued":{"date-parts":["2008"]},"container-title":"South India, Pakistan Journal of Nutrition","volume":"8","issue":"1","page":"83\u201385"}]

[{"id":4294,"citationNumber":"18.","type":"article-journal","title":"Tannin inhibits HIV-1 entry by targeting gp41","DOI":null,"author":[{"given":"L.","family":"L\u00fc"},{"given":"S.-w","family":"Liu"},{"given":"S.-b","family":"Jiang"},{"given":"S.-g","family":"Wu"}],"issued":{"date-parts":["2004"]},"container-title":"Acta Pharmacologica Sinica","volume":"25","issue":"2","page":"213\u2013218"}]

[{"id":4295,"citationNumber":"19.","type":"article-journal","title":"Phytochemical and antioxidant investigations of a Clausena anisata hook, a South African medicinal plant","DOI":null,"author":[{"given":"I.","family":"Lawal"},{"given":"D.","family":"Grierson"},{"given":"A.","family":"Afolayan"}],"issued":{"date-parts":["2015"]},"container-title":"African Journal of Traditional, Complementary and Alternative Medicines","volume":"12","issue":"1","page":"28\u201337"}]

[{"id":4296,"citationNumber":"20.","type":"article-journal","title":"Estimation of alkaloid, saponin and flavonoid, content in various extracts of Crocus sativa","DOI":null,"author":[{"given":"M.A.","family":"Mir"},{"given":"K.","family":"Parihar"},{"given":"U.","family":"Tabasum"},{"given":"E.","family":"Kumari"}],"issued":{"date-parts":["2016"]},"container-title":"Journal of Medicinal Plants Studies","volume":"4","issue":"5","page":"171\u2013174"}]

[{"id":4297,"citationNumber":"21.","type":"article-journal","title":"Determination of total phenol, alkaloid, flavonoid and tannin in different extracts of Calanthe triplicata","DOI":null,"author":[{"given":"K.","family":"Mythili"},{"given":"C.U.","family":"Reddy"},{"given":"D.","family":"Chamundeeswari"},{"given":"P.K.","family":"Manna"}],"issued":{"date-parts":["2014"]},"container-title":"Research & Reviews: Journal of Pharmacognosy and Phytochemistry","volume":"2","issue":"2","page":"40\u201344"}]

[{"id":4298,"citationNumber":"22.","type":"article-journal","title":"Phytochemical analysis and antimalarial activity aqueous extract of Lecaniodiscus cupanioides root","DOI":null,"author":[{"given":"M.O.","family":"Nafiu"},{"given":"T.A.","family":"Abdulsalam"},{"given":"M.A.","family":"Akanji"}],"issued":{"date-parts":["2013"]},"container-title":"Journal of Tropical Medicine","volume":"2013","issue":null,"page":"1\u20134"}]

[{"id":4299,"citationNumber":"23.","type":"article-journal","title":"Phytochemical studies and comparative efficacy of the crude extracts of some haemostatic plants in Edo and Delta states of Nigeria","DOI":null,"author":[{"given":"B.O.","family":"Obadoni"},{"given":"P.O.","family":"Ochuko"}],"issued":{"date-parts":["2002"]},"container-title":"Global Journal of Pure and Applied Sciences","volume":"8","issue":"2","page":"203\u2013208"}]

[{"id":4300,"citationNumber":"24.","type":"article-journal","title":"Aqueous extracts of two tropical ethnobotanicals (Tetrapleura tetraptera and Quassia undulata) improved spatial and non-spatial working memories in scopolamine-induced amnesic rats: Influence of neuronal cholinergic and antioxidant systems","DOI":null,"author":[{"given":"V.O.","family":"Odubanjo"},{"given":"E.O.","family":"Ibukun"},{"given":"G.","family":"Oboh"},{"given":"S.A.","family":"Adefegha"}],"issued":{"date-parts":["2018"]},"container-title":"Biomedicine & Pharmacotherapy","volume":"99","issue":null,"page":"198\u2013204"}]

[{"id":4301,"citationNumber":"25.","type":"article-journal","title":"Anticholinesterase activity and phenolic profile of two medicinal plants ( Quassia undulata and Senecio abyssinicus ) used in managing cognitive dysfunction in Nigeria","DOI":null,"author":[{"given":"V.O.","family":"Odubanjo"},{"given":"G.","family":"Oboh"},{"given":"S.I.","family":"Oyeleye"},{"given":"S.A.","family":"Adefegha"}],"issued":{"date-parts":["2018"]},"container-title":"Journal of Food Biochemistry","volume":"42","issue":"4","page":"12497"}]

[{"id":4302,"citationNumber":"26.","type":"article-journal","title":"Antioxidant and phytochemical properties of Carpobrotus edulis (L.) bolus leaf used for the management of common infections in HIV\/AIDS patients in Eastern Cape province","DOI":null,"author":[{"given":"B.E.","family":"Omoruyi"},{"given":"G.","family":"Bradley"},{"given":"A.J.","family":"Afolayan"}],"issued":{"date-parts":["2012"]},"container-title":"BMC Complementary and Alternative Medicine","volume":"12","issue":"1","page":"1186"}]

[{"id":4303,"citationNumber":"27.","type":"article-journal","title":"Qualitative and quantitative phytochemical evaluations of Strophanthus hispidus stem bark","DOI":null,"author":[{"given":"M.","family":"Osibemhe"},{"given":"I.","family":"Onoagbe"}],"issued":{"date-parts":["2015"]},"container-title":"IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS","volume":"10","issue":"2","page":"120\u2013 124"}]

[{"id":4304,"citationNumber":"28.","type":"chapter","title":"Coumarins and related compounds from the medicinal plants of Africa","DOI":null,"author":[{"given":"H.M.P.","family":"Poumale"},{"given":"R.","family":"Hamm"},{"given":"Y.","family":"Zang"},{"given":"Y.","family":"Shiono"},{"given":"V.","family":"Kuete"}],"issued":{"date-parts":["2013"]},"container-title":"Medicinal Plant Research in Africa","volume":null,"issue":null,"page":"261\u2013300"}]

[{"id":4305,"citationNumber":"29.","type":"article-journal","title":"Studies on qualitative and quantitative phytochemical analysis of Cissus quadrangularis","DOI":null,"author":[{"given":"R.M.","family":"Prabhavathi"},{"given":"M.P.","family":"Prasad"},{"given":"M.","family":"Jayaramu"}],"issued":{"date-parts":["2016"]},"container-title":"Advances in Applied Science Research","volume":"7","issue":"4","page":"11\u201317"}]

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[{"id":4307,"citationNumber":"31.","type":"article-journal","title":"Medicinal plants: Future source of new drugs","DOI":null,"author":[{"given":"A.","family":"Shakya"}],"issued":{"date-parts":["2016"]},"container-title":"International Journal of Herbal Medicine","volume":"4","issue":"4","page":"59\u201364"}]

[{"id":4308,"citationNumber":"32.","type":"article-journal","title":"Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin\u2013Cioc\u00e2lteu reagent","DOI":null,"author":[{"given":"V.L.","family":"Singleton"},{"given":"R.","family":"Orthofer"},{"given":"R.M.","family":"Lamuela-Ravent\u00f3s"}],"issued":{"date-parts":["1999"]},"container-title":"Methods in Enzymology","volume":"299","issue":null,"page":"152\u2013178"}]

[{"id":4309,"citationNumber":"33.","type":"article-journal","title":"Total phenolic content, flavonoid concentration and antioxidant activity of Marrubium peregrinum L. extracts","DOI":null,"author":[{"given":"M.S.","family":"Stankovic"}],"issued":{"date-parts":["2011"]},"container-title":"Kragujevac Journal of Science","volume":"33","issue":null,"page":"63\u201372"}]

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